Increased usage of antacids among GERD patients, silent cause of CVDs, Health News, ET HealthWorld

Increased use of antacids in GERD patients, silent cause of cardiovascular diseaseBy Kivi Lydia Vito

New Delhi: India is witnessing an increase in cardiovascular disease (CVD), mainly due to a sedentary lifestyle and consumption of highly processed unhealthy foods. This has once again come into the limelight as several celebrities have succumbed to CVDs in recent months.

In recent years, the prevalence of gastroesophageal reflux disease (GERD), often known as acidity, has risen to 30 percent among Indians, with Kolkata having the highest acidity and indigestion (38.5 percent) and Surat the lowest (21 percent). . According to researchers from Stanford University and Houston Methodist, those who take proton pump inhibitors such as antacids are 21 percent more likely to have a heart attack than those who don’t. In addition, taking antacids, which cause an irregular heartbeat and the formation of plaque in the arteries, increases the risk of developing cardiovascular disease in people with GERD.

Linking Antacids to CVDs

Antacids are one of the most commonly prescribed over-the-counter medications, and while they are generally safe and well tolerated, they have been linked to cardiovascular disease in people suffering from acid reflux.

The active ingredients of antacid include inhibitors that may be a silent cause of cardiovascular disease in GERD patients, as Dr. Ashish Agarwal, Director of Cardiology, Aakash Healthcare, Dwarka said: “Proton pump inhibitors (PPIs), a form of antacids, are commonly taken for a range of health problems. But they should be careful with their use, as a study found that adults taking it taking the drug are 16-21 percent more likely to have a heart attack than people who don’t take the antacid. PPIs can adversely affect the endothelium, the Teflon-like lining of blood vessels.”

dr. Manish Hinduja, Cardiothoracic and Vascular Surgery Consultant, Fortis Hospital, Mulund added on the link between acidity, antacids and heart attack: “Regular use of PPIs and commonly used antacids. For example, pantoprazole has been linked to coronary artery disease, as shown by a few reports, as chest pain is often confused with acidity.”

“Patients who have prolonged heartburn, even after taking antacids, should also have a heart exam, especially if they show cardiac risk factors.” he added.

dr. Apurva Shah, senior gastroenterologist, Apollo Hospitals, Ahmedabad, said: “Increased use of antacids, proton pump inhibitors can affect cardiovascular health through multiple mechanisms, such as reduction of nitric oxide bioavailability, electrolyte imbalance and interaction with some anti-inflammatory drugs. platelet agents.”

Diets, OTC drugs such as antacids play a role

Under the Drug Regulations of 1945, certain drugs were included in Schedule K of the Act, making drugs available over the counter by licensed retailers, including antacids. The aim of the new policy was to minimize treatment time and costs while encouraging self-care without compromising health, but when such drugs are taken without proper physician guidance, it can contribute to a range of health problems.

Speaking of using antacids as an OTC drug, Dr. Deepak Gupta, medical gastroenterologist, Apollo Hospitals, Navi Mumbai: “It is widely available without a prescription and many patients take it before they see their doctor,” he also mentions that antacids have a market share of at least 20 percent.

“Antacid market is growing. As the pandemic acidity problems have increased and so there has been an increase in the over-the-counter antacids decline,” said Dr. Rakesh Patel, Senior Consultant Gastroenterologist, Fortis Hospital, Kalyan.

dr. Explaining why antacid use has increased by underscoring a person’s diet, Agarwal said: “Lifestyle is one of the most crucial factors behind causing acidity. The most common cause is food. Onions, chocolate, coffee, Cheese and peppermint cause acidity Spicy foods or large meals can also cause anxiety and being overweight also increases acidity.

“The main triggers for GERD are obesity, tobacco consumption or smoking, spicy and non-vegetarian diets, connective tissue disorders, and the use of medications such as antibiotics, NSAIDs, antidepressants and osteoporosis medications,” said Dr. shah.

Staying healthy and preventing disease requires a balanced diet. A healthy diet can improve one’s long-term health, but ignoring the importance of nutrition can also lead to health problems. “The burden of heart disease is increasing at a rapid rate and the main reasons for this are an unhealthy lifestyle, physical inactivity, unhealthy diet, smoking, alcohol consumption, and inappropriate sleep routines,” says Dr. Ankur Phaterpekar, director of Cath Lab and interventional cardiologist. , Symbiosis Hospital, Mumbai.

dr. When asked if Indian food plays a role in acidity, Patel said: “The Indian diet, if followed properly, will not result in GERD. Adding spices, carbonated drinks and fats to the diet leads to acidity.”

Lesser known side effects of antacids

Antacids are over-the-counter medications that efficiently cure acidity and indigestion by neutralizing stomach acid; however, long-term use of these OTC medications can have adverse health effects. Regular use and consumption can lead to calcium and magnesium deficiencies, and long-term use has also been linked to kidney problems and impairing the effectiveness of other medications

dr. Agarwal said: “Many side effects of antacids are caused by not taking them as prescribed. Calcium is found in many antacids. Calcium overdose can occur if one takes too much or for longer than recommended. Too much calcium can lead to nausea, vomiting , changes in mental status and kidney stones. It can also lead to alkalosis, a condition in which the body does not make enough acid to function properly.”

He went on to say that “antacids can only calm the condition, not cure it, and one should always consult a doctor before choosing the right antacid.”

dr. Adding about the safety of taking antacids in everyday life, Gupta said: “Aciders help minimize the symptoms associated with hyperacidity, mainly the burning sensation in the abdomen, bloating and epigastric discomfort, but antacids should not be used on a regular basis.”

“Anti-acid inhibitors (PPI) are safe when taken in the right doses, by the right patient and for the right indication, but if they are used frequently, it will lead to side effects. Side effects such as kidney disease, loss of bone density, opportunistic infections, magnesium deficiency and B12 deficiency. So the medicine should only be used when prescribed, as antacid liquids contain salts that can cause problems if taken unsupervised for a long time,” said Dr. Patel.

dr. Gupta also said, “The regular consumption of antacids is also known to cause kidney problems with long-term use.”

“The use of acid tablets is very widespread among Indians, and long-term use of these tablets can be harmful and have a major impact on health,” Dr. shah.

Antacids are among the most commonly prescribed over-the-counter medications and are generally safe when taken in recommended doses and for their intended purpose, but they can have adverse side effects if used excessively without proper guidance from a physician.

Leave a Comment

Your email address will not be published.