Scientists discover new way of treating solid tumours using Nanoparticles | News

June 20, 2022, 11:28 AM ISTSource: ANI

According to a recent study, a group of researchers at Wake Forest University School of Medicine has found a new way to treat solid tumors with the creation of a new nanoparticle. They also found that cancers of the breast, colon, head and neck have tumors that are solid. In the study, an associate professor of cancer biology at Wake Forest University School of Medicine, Dr. Xin Ming and his team used a nanoparticle to deliver a small molecule called ARL67156 to promote an anti-tumor immune response in mouse models of colon, head and neck, and metastatic breast cancer, resulting in increased survival. The study was published online in a journal called Science Translational Medicine. Although immunotherapy has changed cancer treatment, only about 20% of patients respond to treatment. The presence of adenosine in the tumor microenvironment may lead to a poor therapeutic response. However, the nanoparticle design allows for the accumulation and release of ARL67156 selectively in solid tumors. Ming concluded the study: “Our study suggests that there is a potential translation of our nanoparticle therapy for the treatment of human cancers and that it could also increase the effectiveness of existing treatments. These findings warrant further evaluation.”

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